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I never would have thought someone as healthy as me could get hepatitis B I never would have thought someone as healthy as me could get hepatitis B

It may be difficult to predict who can get hepatitis B, 
which can lead to serious consequences like liver cancer*

Help protect yourself from HBV with HEPLISAV‑B

For most people, HBV clears on its own. But for those who don’t clear the virus, it can cause liver cancer.

*HEPLISAV-B does not treat liver disease, such as cirrhosis and liver cancer
HBV=hepatitis B virus


Why get vaccinated for hepatitis B?

Chronic hepatitis B can lead to serious consequences, 
including diseases like

Liver cancer

Hepatitis B has no cure—vaccination is the best way to prevent it

The CDC recommends that all eligible adults receive hepatitis B vaccination

HEPLISAV-B provides protection 
with 2 doses in 1 month

The first and only 
adult hepatitis B 
vaccine that's just 
2 doses in 1 month

Be sure to complete 
all doses
of your hepatitis B 
vaccine to be protected

Frequently Asked Questions

Healthy or not, unvaccinated people can contract hepatitis B. For most people, hepatitis B clears on its own. For those who don’t clear the virus, the resulting health complications can be lifelong or even deadly. Because there is no way of knowing for sure who will clear the virus and who will not, prevention with vaccination is critical. HEPLISAV-B may not work for everyone. Not all liver cancer is caused by hepatitis B.

You can typically get vaccinated at your pharmacy or doctor's office. Use our pharmacy finder to find a convenient location near you. Once you find one, don’t forget your insurance card and a valid ID.

Depending on your pharmacy, you can schedule your second dose when you get your first, or you can just walk in.

Your vaccination records should tell you, but if you can't find them, you should discuss it with your healthcare provider.

HEPLISAV-B is approved by the FDA and was studied in clinical trials of more than 10,000 patients. The most common side effects reported by patients within 7 days of vaccination with HEPLISAV-B were pain at the site of injection (23%-39%), tiredness (11%-17%), and headache (8%-17%).

You are encouraged to report vaccine adverse events to the US Department of Health and Human Services. Visit to file a report, or call 1-800-822-7967.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-332-1088.

Most insurance plans cover HEPLISAV-B. Ask your doctor or pharmacist about vaccination coverage and reimbursement to learn more.

Schedule your vaccination today with HEPLISAV-B

HEPLISAV-B is the only adult hepatitis B vaccine that provides protection with just 2 doses in 1 month

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Inclusion of pharmacy information in this finder is based on available data at the time of posting and does not guarantee supply, nor does it represent an endorsement, referral, or recommendation from Dynavax. Please be sure to contact the pharmacy of your choice to check their availability of HEPLISAV-B.

Vaccination with HEPLISAV-B may not protect all individuals

The CDC recommends hepatitis B vaccination for all adults aged 19–59 and for adults aged ≥60 years with risk factors. Adults aged ≥60 years without risk factors may receive hepatitis B vaccination. This recommendation applies to adults who have not received a complete hepatitis B vaccine series in their lifetime.

CDC=Centers for Disease Control and Prevention


HEPLISAV-B is a shot given to adults 18 years of age and older to help prevent infection caused by the hepatitis B virus.

HEPLISAV-B is usually given in the arm muscle. HEPLISAV-B is given in 2 doses, 1 month apart, by a healthcare provider.

If you have a history of severe allergic reaction after a previous dose of any hepatitis B vaccine, or to any ingredient of HEPLISAV-B, including yeast, do not take HEPLISAV-B.

HEPLISAV-B must be given by a medical professional, who will monitor you afterwards, to check for allergic reaction.

If you are immunocompromised, or receiving immunosuppressant therapy, you may have less of an immune response to HEPLISAV-B.

Some people have hepatitis B infection without being aware of it or showing any symptoms. If you already have hepatitis B present in your body, HEPLISAV-B may not prevent hepatitis B infection.

The most common side effects include pain at the injection site, tiredness, and headache.

HEPLISAV-B was not studied in pregnant or nursing women. Tell your provider if you are pregnant or plan to become pregnant or are breastfeeding.

Vaccination with HEPLISAV-B may not protect all individuals.

Talk to your healthcare provider to determine if HEPLISAV-B is right for you.

HEPLISAV-B does not treat liver diseases such as cirrhosis or liver cancer.

Not all liver cancer is caused by the hepatitis B virus.

Please see full Prescribing Information